Junko Hasegawa Selected Research

Analgesics (Analgesic Drugs)

1/2022	Short Tandem Repeat Variation in the CNR1 Gene Associated With Analgesic Requirements of Opioids in Postoperative Pain Management.
1/2018	Association between the rs7583431 single nucleotide polymorphism close to the activating transcription factor 2 gene and the analgesic effect of fentanyl in the cold pain test.
10/2016	Opposite Associations Between the rs3845446 Single-Nucleotide Polymorphism of the CACNA1E Gene and Postoperative Pain-Related Phenotypes in Gastrointestinal Surgery Versus Previously Reported Orthognathic Surgery.
1/2016	Genome-wide association study identifies candidate loci associated with postoperative fentanyl requirements after laparoscopic-assisted colectomy.
1/2016	Association between UGT2B7 gene polymorphisms and fentanyl sensitivity in patients undergoing painful orthognathic surgery.
12/2014	Haplotypes of P2RX7 gene polymorphisms are associated with both cold pain sensitivity and analgesic effect of fentanyl.
1/2014	Association between KCNJ6 (GIRK2) gene polymorphism rs2835859 and post-operative analgesia, pain sensitivity, and nicotine dependence.
1/2013	Association between genetic polymorphisms of the β1-adrenergic receptor and sensitivity to pain and fentanyl in patients undergoing painful cosmetic surgery.
1/2013	Association between genetic polymorphisms in Ca(v)2.3 (R-type) Ca2+ channels and fentanyl sensitivity in patients undergoing painful cosmetic surgery.
12/2009	Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery.

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Junko Hasegawa Research Topics

Disease

20	Pain (Aches) 12/2023 - 12/2009
5	Postoperative Pain 01/2022 - 12/2009
4	Tobacco Use Disorder (Nicotine Dependence) 10/2020 - 01/2014
3	Chronic Pain 12/2023 - 09/2009
3	Inflammation (Inflammations) 12/2023 - 01/2018
3	Neuralgia (Stump Neuralgia) 01/2023 - 01/2018
2	Peripheral Nervous System Diseases (PNS Diseases) 04/2020 - 06/2017
2	Pneumococcal Infections 03/2017 - 08/2015
2	Psychotic Disorders (Schizoaffective Disorder) 08/2015 - 10/2004
1	Autoimmune Diseases (Autoimmune Disease) 12/2023
1	Nausea 09/2023
1	Vomiting 09/2023
1	Cancer Pain 09/2022
1	Herpes Zoster 01/2021
1	Prognathism 01/2021
1	Schizophrenia (Dementia Praecox) 11/2020
1	Ovarian Neoplasms (Ovarian Cancer) 04/2020
1	Neoplasms (Cancer) 01/2018
1	Hypersensitivity (Allergy) 01/2018
1	Ulcerative Colitis 01/2018
1	Rheumatoid Arthritis 01/2018
1	Neuroinflammatory Diseases 01/2018
1	Peripheral Nerve Injuries 01/2018
1	Breast Neoplasms (Breast Cancer) 06/2017
1	Goiter 08/2015
1	Dyspepsia (Indigestion) 11/2011
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 08/2011
1	Parkinson Disease (Parkinson's Disease) 12/2006
1	Alcoholism (Alcohol Abuse) 01/2006

Drug/Important Bio-Agent (IBA)

12	Opioid Analgesics (Opioids)IBA 09/2022 - 09/2009
11	Analgesics (Analgesic Drugs)IBA 01/2022 - 09/2009
8	Fentanyl (Sublimaze)FDA LinkGeneric 01/2022 - 12/2009
2	Interleukin-17 (Interleukin 17)IBA 12/2023 - 01/2018
2	PAR-2 ReceptorIBA 12/2023 - 01/2021
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2014
2	Conjugate VaccinesIBA 03/2017 - 08/2015
2	Methamphetamine (Desoxyn)FDA LinkGeneric 08/2015 - 10/2004
2	alpha-SynucleinIBA 12/2006 - 10/2004
1	Propofol (Diprivan)FDA LinkGeneric 09/2023
1	NucleotidesIBA 01/2022
1	Purinergic P2Y12 ReceptorsIBA 01/2022
1	Protein Kinase C-thetaIBA 01/2021
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2021
1	SmokeIBA 11/2020
1	Nicotine FDA Link 10/2020
1	levodopa receptorIBA 10/2020
1	taxaneIBA 04/2020
1	Sodium Channels (Sodium Channel)IBA 04/2020
1	CytokinesIBA 01/2018
1	Activating Transcription Factor 2IBA 01/2018
1	ChemokinesIBA 01/2018
1	human ATF2 proteinIBA 01/2018
1	Cytochrome P-450 CYP2C8IBA 06/2017
1	Paclitaxel (Taxol)FDA LinkGeneric 06/2017
1	Calcium Channels (Calcium Channel)IBA 10/2016
1	Morphine (MS Contin)FDA LinkGeneric 01/2016
1	tyramine-deoxysorbitolIBA 08/2015
1	OrexinsIBA 08/2015
1	Orexin ReceptorsIBA 08/2015
1	Purinergic P2X7 ReceptorsIBA 12/2014
1	Dopamine Receptors (Dopamine Receptor)IBA 01/2014
1	GTP-Binding Proteins (G-Protein)IBA 01/2014
1	PotassiumIBA 01/2014
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2013
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2013
1	Z 338IBA 11/2011
1	Mesalamine (Mesalazine)FDA LinkGeneric 08/2011
1	3' Untranslated Regions (3' UTR)IBA 12/2009
1	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2006

Therapy/Procedure

4	Colectomy 05/2023 - 10/2016
4	Analgesia 01/2022 - 01/2013
3	Orthognathic Surgery 01/2021 - 10/2016
2	Tooth Extraction (Tooth Extractions) 01/2023 - 01/2022
2	Pulpectomy 01/2023 - 01/2022
1	Precision Medicine 12/2023
1	Palliative Care (Palliative Therapy) 09/2022
1	Sagittal Split Ramus Osteotomy 01/2021
1	Patient-Controlled Analgesia (Analgesia, Patient Controlled) 10/2016
1	Epidural Analgesia 10/2016
1	Operative Surgical Procedures 01/2016